Several medications containing Losartan are being recalled. (Black Press file photo)

Potential ‘human carcinogen’ leads to recall of Losartan-containing drugs

Health Canada is advising that there is no immediate risk to patients taking these medications

Multiple high blood pressure medications containing Losartan are being voluntarily recalled due to a “potentially human carcinogen,” Health Canada says.

Teva Canada, Apotex Inc., Pharmascience Inc,m and Pro Doc Limitée are recalling lots of Losartan-containing drugs because of the potential for a nitrosamine impurity, N-Nitroso-N-methyl-4-aminobutyric acid (NMBA) – a potential human carcinogen meaning that long-term exposure could increase the potential risk of cancer.

As with previous recalls involving nitrosamine impurities, Health Canada is advising that there is no immediate risk to patients taking these medications since the potential risk of cancer is with long-term exposure to the impurities.

“Patients should not stop taking their medication unless advised to do so by their healthcare provider,” Health Canada says.

Teva Canada is voluntarily recalling two lots of combination Losartan/hydrochlorothiazide (HCTZ) tablets after testing of one lot identified levels of NMBA above what is considered reasonably safe if the drug were taken over a lifetime. Apotex Inc., Pharmascience Inc., and Pro Doc Limitée are voluntarily recalling multiple lots of Losartan-containing products as a precaution.

The Losartan active pharmaceutical ingredient (API) in all of the recalled products is manufactured by Hetero Labs Ltd. Unit 1, in India. These recalls represent all lots of drugs distributed in Canada that contain Losartan API manufactured at Hetero Labs Ltd. Unit 1.

Related: Children’s strawberry-flavoured medicines recalled due to faulty safety cap

Related: Brewer’s yeast recall for peanut allergies

Losartan is an angiotensin receptor blocker (ARB) drug, also known as a “sartan.” Sartans are a class of drugs used to treat patients with high blood pressure to help prevent heart attacks and stroke. They are also used in patients who have had heart failure or a recent heart attack. There have been multiple recalls of products containing another sartan, valsartan, in Canada and internationally since July 2018 because of nitrosamine impurities (see links below for more information).

There are alternative products currently available on the Canadian market.

Health Canada continues to monitor the supply situation. Health Canada encourages Canadians to visit drugshortagescanada.ca for information on drug shortages and discontinuances. Patients with questions or concerns about any drug they are taking, including on what to do if that drug is not readily available, should speak to their healthcare professional.

For a list of affected products, visit healthycanadians.gc.ca.


@VernonNews
newstips@vernonmorningstar.com

Like us on Facebook and follow us on Twitter.

Just Posted

Foundation being built for the new Chemainus library to become a cornerstone of the community

All the services and amenities in keeping with the modern age

Teddy the dog trial postponed for two weeks in Duncan

Defence counsel withdraws due to “personal tragedy”

Caps fall to Wild in game two

Cowichan earns a split in Wenatchee

Caps win game one against Wild

Cowichan draws first blood in Interior semifinal

VIDEO: RCMP ask kids to help name soon-to-be police dogs

13 German shepherd puppies will be born this year

NDP’s Jagmeet Singh steps into the House of Commons, making history

Burnaby South MP becomes first visible minority to lead a federal party in the House of Commons

Reeling Port Alice about to lose its only bank

Scotiabank branch closure follows latest mill setback, bad for business and the elderly

Simard guilty in Vancouver Island double murder

Convicted of two counts of second-degree murder in 2016 killing of Courtenay couple

Crab poaching under cover of darkness earns 10-year commercial fishing ban, vessel seizure

A Cape Mudge resident involved in poaching dungeness crabs in Vancouver Harbour… Continue reading

‘Considerably large’ tractor tire fell and killed 3-year-old girl on B.C. farm

Delta’s deputy fire chief said crews tried to helicopter girl out after a tractor tire leaning against a barn fell onto her

Nearly 40% of British Columbians not taking their medications correctly: poll

Introduction of legal cannabis could cause more issues for drug interactions

Mining company fined $70,000 after two workers killed in B.C. truck crash

Broda Construction pleaded guilty to failing to provide safe workplace at Cranbrook rock quarry

B.C. argues it cannot stop Trans Mountain, but it can protect environment

Alberta Premier Rachel Notley says only Ottawa has the authority to decide what goes in trans-boundary pipelines

Most Read